EDIT
: Thanks to Bodertz for clearing up some mistakes I made in my original feedback.
MSPA's intended "look" for below-panel text (per this archived Tumblr post: https://wheals.github.io/tumblr/tumblr.html#font-size) is "Aliased, 14 point, bolded Courier New". Certain text effects - like the corrupted pesterlogs in act six - were designed with this look in mind. The current Homestuck.com sets its default below-panel font size to your browser's default font size, making those effects a little less seamless if your browser default isn't 14px.
Andrew says it "isn’t a big deal" if text doesn't appear "the right way". However, it was a default incorporated into the original MSPA site, and I think it's worth incorporating into the current one.